Version 5.4
Mus musculus Gene: Stx4a
Summary
InnateDB Gene IDBG-210404.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stx4a
Gene Name syntaxin 4A (placental)
Synonyms Stx4; Syn-4; Syn4
Species Mus musculus
Ensembl Gene ENSMUSG00000030805
Encoded Proteins
IDBP-210406
syntaxin 4A (placental)
IDBP-400188
syntaxin 4A (placental)
IDBP-538884
syntaxin 4A (placental)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103496:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:127824294-127849019
Strand Forward strand
Band F3
Transcripts
ENSMUST00000033075 ENSMUSP00000033075
ENSMUST00000121705 ENSMUSP00000112927
ENSMUST00000152310
ENSMUST00000138399
ENSMUST00000156537 ENSMUSP00000118034
ENSMUST00000138294
ENSMUST00000142849
ENSMUST00000123180
ENSMUST00000125861
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 27 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000149 SNARE binding
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0016079 synaptic vesicle exocytosis
GO:0016192 vesicle-mediated transport
GO:0035493 SNARE complex assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0031201 SNARE complex
GO:0035749 myelin sheath adaxonal region
GO:0042581 specific granule
GO:0043219 lateral loop
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000103496
View Gene Order
ENSBTAG00000007523
Not yet available
Pathways
NETPATH
REACTOME
REACT_224553
Hemostasis pathway
REACT_209837
Membrane Trafficking pathway
REACT_224879
Platelet activation, signaling and aggregation pathway
REACT_215302
Disinhibition of SNARE formation pathway
REACT_243409
trans-Golgi Network Vesicle Budding pathway
REACT_234979
Clathrin derived vesicle budding pathway
REACT_206166
Response to elevated platelet cytosolic Ca2+ pathway
REACT_199054
Translocation of GLUT4 to the plasma membrane pathway
KEGG
mmu04130
SNARE interactions in vesicular transport pathway
mmu04962
Vasopressin-regulated water reabsorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_1178
Disinhibition of SNARE formation pathway
REACT_1280
Response to elevated platelet cytosolic Ca2+ pathway
REACT_147867
Translocation of GLUT4 to the plasma membrane pathway
REACT_19187
Clathrin derived vesicle budding pathway
REACT_11235
trans-Golgi Network Vesicle Budding pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_604
Hemostasis pathway
REACT_11123
Membrane Trafficking pathway
REACT_217718
Translocation of GLUT4 to the plasma membrane pathway
REACT_212196
Hemostasis pathway
REACT_209572
Platelet activation, signaling and aggregation pathway
REACT_212308
Response to elevated platelet cytosolic Ca2+ pathway
REACT_216751
Clathrin derived vesicle budding pathway
REACT_211153
trans-Golgi Network Vesicle Budding pathway
REACT_220570
Disinhibition of SNARE formation pathway
REACT_213260
Membrane Trafficking pathway
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
hsa04962
Vasopressin-regulated water reabsorption pathway
INOH
PID NCI
ecadherin_stabilization_pathway
Stabilization and expansion of the E-cadherin adherens junction
insulin_glucose_pathway
Insulin-mediated glucose transport
Cross-References
SwissProt P70452
TrEMBL
UniProt Splice Variant
Entrez Gene 20909
UniGene Mm.24867
RefSeq NM_009294
OMIM
CCDS CCDS21880
HPRD
IMGT
MGI ID MGI:893577
MGI Symbol Stx4a
EMBL AK145909 AK161971 BC005791 BC011491 BC052023 U76832
GenPept AAB18991 AAH05791 AAH11491 AAH52023 BAE26743 BAE36660
RNA Seq Atlas 20909

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca