Version 5.4
Homo sapiens Gene: STX4
Summary
InnateDB Gene IDBG-27565.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STX4
Gene Name syntaxin 4
Synonyms p35-2; STX4A
Species Homo sapiens
Ensembl Gene ENSG00000103496
Encoded Proteins
IDBP-27567
syntaxin 4
IDBP-240446
syntaxin 4
IDBP-375711
syntaxin 4
IDBP-747487
IDBP-749535
IDBP-806949
syntaxin 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:31032889-31042975
Strand Forward strand
Band p11.2
Transcripts
ENST00000313843 ENSP00000317714
ENST00000394998 ENSP00000378447
ENST00000457779 ENSP00000390788
ENST00000503629
ENST00000493902
ENST00000487411
ENST00000496977 ENSP00000454841
ENST00000460668 ENSP00000454419
ENST00000461455
ENST00000478150
ENST00000486660
ENST00000475862
ENST00000468583
ENST00000566353
ENST00000564368
ENST00000565483
ENST00000613541 ENSP00000480544
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 43 [view]
Protein-Protein 43 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000149 SNARE binding
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
Biological Process
GO:0006836 neurotransmitter transport
GO:0006886 intracellular protein transport
GO:0006892 post-Golgi vesicle-mediated transport
GO:0007596 blood coagulation
GO:0016192 vesicle-mediated transport
GO:0030168 platelet activation
GO:0035493 SNARE complex assembly
GO:0061024 membrane organization
Cellular Component
GO:0005737 cytoplasm
GO:0005773 vacuole
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0031201 SNARE complex
GO:0035749 myelin sheath adaxonal region
GO:0042581 specific granule
GO:0043219 lateral loop
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030805
View Gene Order
ENSBTAG00000007523
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_1178
Disinhibition of SNARE formation pathway
REACT_1280
Response to elevated platelet cytosolic Ca2+ pathway
REACT_147867
Translocation of GLUT4 to the plasma membrane pathway
REACT_19187
Clathrin derived vesicle budding pathway
REACT_11235
trans-Golgi Network Vesicle Budding pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_604
Hemostasis pathway
REACT_11123
Membrane Trafficking pathway
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
hsa04962
Vasopressin-regulated water reabsorption pathway
INOH
PID NCI
ecadherin_stabilization_pathway
Stabilization and expansion of the E-cadherin adherens junction
insulin_glucose_pathway
Insulin-mediated glucose transport
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.733645 Hs.83734
RefSeq NM_001272095 NM_001272096 NM_004604 XM_005255521
HUGO
OMIM
CCDS CCDS10700 CCDS61916
HPRD 01722
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca