InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Acss2

Summary

InnateDB Gene

IDBG-210603.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Acss2

Gene Name

acyl-CoA synthetase short-chain family member 2

Synonyms

1110017C11Rik; ACAS; Acas1; Acas2; AceCS1; Acs1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000027605

Encoded Proteins

IDBP-210605

acyl-CoA synthetase short-chain family member 2

IDBP-210607

acyl-CoA synthetase short-chain family member 2

IDBP-210609

acyl-CoA synthetase short-chain family member 2

IDBP-533116

acyl-CoA synthetase short-chain family member 2

IDBP-534589

acyl-CoA synthetase short-chain family member 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131069:
This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:155517948-155585724

Strand

Forward strand

Band

Transcripts

ENSMUST00000103142	ENSMUSP00000099431
ENSMUST00000029135	ENSMUSP00000029135
ENSMUST00000065973	ENSMUSP00000068776
ENSMUST00000149788
ENSMUST00000133654	ENSMUSP00000116501
ENSMUST00000131054
ENSMUST00000143169
ENSMUST00000151781	ENSMUSP00000122545
ENSMUST00000153975
ENSMUST00000148870

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003987	acetate-CoA ligase activity
GO:0005524	ATP binding

Biological Process

GO:0006085	acetyl-CoA biosynthetic process
GO:0008152	metabolic process
GO:0008610	lipid biosynthetic process
GO:0019413	acetate biosynthetic process
GO:0019542	propionate biosynthetic process