Homo sapiens Gene: ACSS2 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-68854.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | ACSS2 | ||||||||||||||||||
Gene Name | acyl-CoA synthetase short-chain family member 2 | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000131069 | ||||||||||||||||||
Encoded Proteins |
acyl-CoA synthetase short-chain family member 2
acyl-CoA synthetase short-chain family member 2
acyl-CoA synthetase short-chain family member 2
acyl-CoA synthetase short-chain family member 2
acyl-CoA synthetase short-chain family member 2
acyl-CoA synthetase short-chain family member 2
acyl-CoA synthetase short-chain family member 2
acyl-CoA synthetase short-chain family member 2
acyl-CoA synthetase short-chain family member 2
acyl-CoA synthetase short-chain family member 2
acyl-CoA synthetase short-chain family member 2
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 20:34872146-34927962 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | q11.22 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
Ethanol oxidation pathway
Metabolism pathway
Biological oxidations pathway
Phase 1 - Functionalization of compounds pathway
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KEGG |
Glycolysis / Gluconeogenesis pathway
Pyruvate metabolism pathway
Propanoate metabolism pathway
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INOH |
Propanoate metabolism pathway
Pyruvate metabolism pathway
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PID NCI |
Signaling events mediated by HDAC Class III
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Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | |||||||||||||||||||
UniGene | Hs.517034 | ||||||||||||||||||
RefSeq | NM_001076552 NM_001242393 NM_018677 | ||||||||||||||||||
HUGO | |||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS13243 CCDS42868 | ||||||||||||||||||
HPRD | |||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | |||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||