Version 5.4
Mus musculus Gene: L3mbtl1
Summary
InnateDB Gene IDBG-211789.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol L3mbtl1
Gene Name l(3)mbt-like (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000035576
Encoded Proteins
IDBP-211791
l(3)mbt-like (Drosophila)
IDBP-537155
l(3)mbt-like (Drosophila)
IDBP-541965
l(3)mbt-like (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185513:
This gene represents a polycomb group gene. The encoded protein functions to regulate gene activity, likely via chromatin modification. The encoded protein may also be necessary for mitosis. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:162943472-162974522
Strand Forward strand
Band H2
Transcripts
ENSMUST00000035751 ENSMUSP00000044038
ENSMUST00000153416
ENSMUST00000156954 ENSMUSP00000123217
ENSMUST00000137108
ENSMUST00000149447
ENSMUST00000124264 ENSMUSP00000116118
ENSMUST00000125296
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 0
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0031491 nucleosome binding
GO:0031493 nucleosomal histone binding
GO:0032093 SAM domain binding
GO:0035064 methylated histone binding
GO:0042393 histone binding
GO:0042802 identical protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007088 regulation of mitosis
GO:0016568 chromatin modification
GO:0030097 hemopoiesis
GO:0040029 regulation of gene expression, epigenetic
GO:0045652 regulation of megakaryocyte differentiation
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0000785 chromatin
GO:0000793 condensed chromosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000185513
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.187086
RefSeq NM_001081338 XM_006499527 XM_006499528 XM_006499529
OMIM
CCDS CCDS38314
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca