Mus musculus Gene: Wfdc3
Summary
InnateDB Gene IDBG-212302.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wfdc3
Gene Name WAP four-disulfide core domain 3
Synonyms 1700015L13Rik; 1700127F16Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000076434
Encoded Proteins
WAP four-disulfide core domain 3
WAP four-disulfide core domain 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124116:
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains four WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Alternatively spliced transcript variants have been observed but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:164731180-164745931
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000103096 ENSMUSP00000099385
ENSMUST00000109328 ENSMUSP00000104951
ENSMUST00000130227
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0030414 peptidase inhibitor activity
Biological Process
GO:0008150 biological_process
GO:0010466 negative regulation of peptidase activity
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q14AE4
TrEMBL A2A4Y5
UniProt Splice Variant
Entrez Gene 71856
UniGene Mm.482906
RefSeq NM_027961 XM_006500192 XM_006500193 XM_006500194
OMIM
CCDS CCDS17053
HPRD
IMGT
MGI ID MGI:1923897
MGI Symbol Wfdc3
EMBL AL591127 BC116847 BC116875 CH466551
GenPept AAI16848 AAI16876 CAM22415 EDL06411
RNA Seq Atlas 71856