Version 5.4
Bos taurus Gene: WFDC3
Summary
InnateDB Gene IDBG-642955.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WFDC3
Gene Name Uncharacterized protein; Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016742
Encoded Proteins
IDBP-695466
WAP four-disulfide core domain 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124116:
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains four WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Alternatively spliced transcript variants have been observed but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:75267859-75284423
Strand Reverse strand
Band
Transcripts
ENSBTAT00000022259 ENSBTAP00000022259
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0030414 peptidase inhibitor activity
Biological Process
GO:0010466 negative regulation of peptidase activity
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000124116
View Gene Order
ENSMUSG00000076434
View Gene Order
Cross-References
SwissProt
TrEMBL F1MPI5
UniProt Splice Variant
Entrez Gene 505523
UniGene Bt.109687 Bt.34215
RefSeq NM_001104966 XM_005214552 XM_005214553
HUGO HGNC:15957
OMIM
CCDS
HPRD
IMGT
EMBL AAFC03033641 AAFC03071788
GenPept
RNA Seq Atlas 505523

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca