Version 5.4
Mus musculus Gene: Tnnc2
Summary
InnateDB Gene IDBG-212329.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tnnc2
Gene Name troponin C2, fast
Synonyms Tncs
Species Mus musculus
Ensembl Gene ENSMUSG00000017300
Encoded Proteins
IDBP-212331
troponin C2, fast
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101470:
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:164777161-164779967
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000103095 ENSMUSP00000099384
ENSMUST00000155443
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005509 calcium ion binding
Biological Process
GO:0003009 skeletal muscle contraction
GO:0007165 signal transduction
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005861 troponin complex
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000101470
View Gene Order
Pathways
NETPATH
REACTOME
REACT_232053
Striated Muscle Contraction pathway
REACT_262759
Muscle contraction pathway
KEGG
mmu04020
Calcium signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_16969
Striated Muscle Contraction pathway
REACT_17044
Muscle contraction pathway
KEGG
hsa04020
Calcium signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt P20801
TrEMBL
UniProt Splice Variant
Entrez Gene 21925
UniGene
RefSeq NM_009394
OMIM
CCDS CCDS17056
HPRD
IMGT
MGI ID MGI:98780
MGI Symbol Tnnc2
EMBL BC024390 M57590
GenPept AAA37642 AAH24390
RNA Seq Atlas 21925

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca