Version 5.4
| Mus musculus Gene: Pltp | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Gene | IDBG-212419.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Pltp | ||||||||
| Gene Name | phospholipid transfer protein | ||||||||
| Synonyms | Bpife; OD107 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000017754 | ||||||||
| Encoded Proteins |
phospholipid transfer protein
phospholipid transfer protein
phospholipid transfer protein
phospholipid transfer protein
phospholipid transfer protein
|
||||||||
| Protein Structure |
|
||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| InnateDB Annotation | |||||||||
| Summary |
Pltp may play a pivotal role in inflammation and innate immunity through its ability to accelerate the 'reverse LPS transport' pathway.
|
||||||||
| InnateDB Annotation from Orthologs | |||||||||
| Summary |
[Homo sapiens] PLTP may play a pivotal role in inflammation and innate immunity through its ability to accelerate the 'reverse LPS transport' pathway. (Demonstrated in mouse)
|
||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100979:
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
||||||||
| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 2:164839518-164857711 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | H3 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Orthologs | |||||||||
|
Species
Homo sapiens
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||
| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
HDL-mediated lipid transport pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Lipid digestion, mobilization, and transport pathway
Lipoprotein metabolism pathway
|
||||||||
| KEGG |
PPAR signaling pathway pathway
|
||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
PPAR signaling pathway pathway
|
||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | P55065 | ||||||||
| TrEMBL | A2A5K2 A2A5K3 A2A5K4 Q3UE59 Q3UFS5 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 18830 | ||||||||
| UniGene | Mm.6105 | ||||||||
| RefSeq | NM_011125 XM_006498952 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS17063 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:103151 | ||||||||
| MGI Symbol | Pltp | ||||||||
| EMBL | AK148330 AK149730 AL591495 BC003782 CH466551 U28960 U37226 | ||||||||
| GenPept | AAA80542 AAA87943 AAH03782 BAE28485 BAE29052 EDL06430 | ||||||||
| RNA Seq Atlas | 18830 | ||||||||