Mus musculus Gene: Arhgap27
Summary
InnateDB Gene IDBG-213021.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgap27
Gene Name Rho GTPase activating protein 27
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000034255
Encoded Proteins
Rho GTPase activating protein 27
Rho GTPase activating protein 27
Rho GTPase activating protein 27
Rho GTPase activating protein 27
Rho GTPase activating protein 27
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159314:
Rho (see ARHA; MIM 165390)-like small GTPases are involved in many cellular processes, and they are inactive in the GDP-bound state and active in the GTP-bound state. GTPase-activating proteins, such as ARHGAP27, inhibit Rho-like proteins by stimulating their intrinsic GTPase activity (Katoh and Katoh, 2004 [PubMed 15492870]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:103331497-103363692
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000041385 ENSMUSP00000039427
ENSMUST00000092557 ENSMUSP00000102637
ENSMUST00000107024 ENSMUSP00000102639
ENSMUST00000107023 ENSMUSP00000102638
ENSMUST00000116102
ENSMUST00000150122
ENSMUST00000144194
ENSMUST00000139830
ENSMUST00000124490
ENSMUST00000136491 ENSMUSP00000128051
ENSMUST00000163250
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017124 SH3 domain binding
GO:0030675 Rac GTPase activator activity
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0007165 signal transduction
GO:0032855 positive regulation of Rac GTPase activity
GO:0043089 positive regulation of Cdc42 GTPase activity
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.259113 Mm.397197
RefSeq NM_001205236 NM_133715 NM_183288 XM_006533754
OMIM
CCDS CCDS25517 CCDS36350 CCDS56815
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas