Version 5.4
Mus musculus Gene: Pard6b
Summary
InnateDB Gene IDBG-213102.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pard6b
Gene Name par-6 (partitioning defective 6) homolog beta (C. elegans)
Synonyms AV025615; Par6b
Species Mus musculus
Ensembl Gene ENSMUSG00000044641
Encoded Proteins
IDBP-213104
par-6 (partitioning defective 6) homolog beta (C. elegans)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124171:
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:168081004-168101203
Strand Forward strand
Band H3
Transcripts
ENSMUST00000052125 ENSMUSP00000052619
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006461 protein complex assembly
GO:0007049 cell cycle
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005923 tight junction
GO:0005938 cell cortex
GO:0043234 protein complex
GO:0045177 apical part of cell
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124171
View Gene Order
ENSBTAG00000021601
Not yet available
Pathways
NETPATH
REACTOME
REACT_248094
Cell-cell junction organization pathway
REACT_241978
Cell junction organization pathway
REACT_236746
Tight junction interactions pathway
REACT_223082
Cell-Cell communication pathway
KEGG
mmu04530
Tight junction pathway
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19373
Tight junction interactions pathway
REACT_111155
Cell-Cell communication pathway
REACT_20676
Cell junction organization pathway
REACT_19331
Cell-cell junction organization pathway
KEGG
hsa04530
Tight junction pathway
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt Q9JK83
TrEMBL
UniProt Splice Variant
Entrez Gene 58220
UniGene Mm.292834
RefSeq NM_021409
OMIM
CCDS CCDS17108
HPRD
IMGT
MGI ID MGI:2135605
MGI Symbol Pard6b
EMBL AF252291 AL831766 BC025147 CH466551
GenPept AAF71528 AAH25147 CAM17536 EDL06536
RNA Seq Atlas 58220

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca