Homo sapiens Gene: KIAA1267
Summary
InnateDB Gene IDBG-55420.6
Last Modified 2013-04-25 [Report errors or provide feedback]
Gene Symbol KIAA1267
Gene Name KAT8 regulatory NSL complex subunit 1
Synonyms CENP-36; hMSL1v1; KDVS; KIAA1267; MSL1v1; NSL1;
Species Homo sapiens
Ensembl Gene ENSG00000120071
Encoded Proteins
KIAA1267
KIAA1267
KIAA1267
Protein Structure
Entrez Gene
Summary This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The corresponding protein in Drosophila interacts with K(lysine) acetyltransferase 8, which is also a subunit of both the MLL1 and NSL1 complexes. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:44107282-44302733
Strand Reverse strand
Band q21.31
Transcripts
ENST00000262419 ENSP00000262419
ENST00000393476 ENSP00000377117
ENST00000432791 ENSP00000387393
ENST00000572904 ENSP00000461484
ENST00000573286
ENST00000576248
ENST00000576870
ENST00000572218
ENST00000574590 ENSP00000461812
ENST00000571698 ENSP00000459330
ENST00000575318 ENSP00000461299
ENST00000574655 ENSP00000459359
ENST00000574963
ENST00000577114
ENST00000572679
ENST00000576739 ENSP00000459627
ENST00000573682
ENST00000576137
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
Experimentally validated
Total 40 [view]
Protein-Protein 40 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043995 histone acetyltransferase activity (H4-K5 specific)
GO:0043996 histone acetyltransferase activity (H4-K8 specific)
GO:0046972 histone acetyltransferase activity (H4-K16 specific)
Biological Process
GO:0043981 histone H4-K5 acetylation
GO:0043982 histone H4-K8 acetylation
GO:0043984 histone H4-K16 acetylation
Cellular Component
GO:0000123 histone acetyltransferase complex
GO:0005634 nucleus
GO:0071339 MLL1 complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q7Z3B3
TrEMBL E9PCT4 I3L233 I3L243 I3L4J3
UniProt Splice Variant
Entrez Gene 284058
UniGene Hs.618377 Hs.619321 Hs.630341 Hs.648744 Hs.690905 Hs.700846
RefSeq NM_001193465 NM_001193466 NM_015443
HUGO 24565
OMIM 612452
CCDS CCDS11503
HPRD 11254
IMGT
EMBL AB033093 AC217773 AK291259 AL117476 AL137317 BC035892 BC098376 BX538006 BX648760 CR936218
GenPept AAH35892 AAH98376 BAA86581 BAF83948 CAB55949 CAB70694 CAD97958 CAH10565
ImmGen KIAA1267 (murine)
RNA Seq Atlas 284058