Version 5.4
Mus musculus Gene: Tcea2
Summary
InnateDB Gene IDBG-214196.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tcea2
Gene Name transcription elongation factor A (SII), 2
Synonyms AI326274; S-II-T1; SII-T1; Tceat
Species Mus musculus
Ensembl Gene ENSMUSG00000059540
Encoded Proteins
IDBP-214198
transcription elongation factor A (SII), 2
IDBP-542584
transcription elongation factor A (SII), 2
IDBP-542586
transcription elongation factor A (SII), 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171703:
The protein encoded by this gene is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:181680310-181688071
Strand Forward strand
Band H4
Transcripts
ENSMUST00000103042 ENSMUSP00000099331
ENSMUST00000129686
ENSMUST00000129745 ENSMUSP00000119646
ENSMUST00000129006 ENSMUSP00000120083
ENSMUST00000126623
ENSMUST00000136145
ENSMUST00000125892
ENSMUST00000126844
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0032784 regulation of DNA-templated transcription, elongation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005813 centrosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000171703
View Gene Order
ENSBTAG00000021836
Not yet available
Cross-References
SwissProt
TrEMBL B7ZCS4
UniProt Splice Variant
Entrez Gene 21400
UniGene Mm.24245
RefSeq XM_006500587 NM_009326
OMIM
CCDS CCDS17219
HPRD
IMGT
MGI ID MGI:107368
MGI Symbol Tcea2
EMBL AL844529
GenPept
RNA Seq Atlas 21400

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca