Version 5.4
Mus musculus Gene: Exoc7
Summary
InnateDB Gene IDBG-214441.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Exoc7
Gene Name exocyst complex component 7
Synonyms Exo70; sec70
Species Mus musculus
Ensembl Gene ENSMUSG00000020792
Encoded Proteins
IDBP-214445
exocyst complex component 7
IDBP-268804
exocyst complex component 7
IDBP-268806
exocyst complex component 7
IDBP-535989
exocyst complex component 7
IDBP-539757
exocyst complex component 7
IDBP-535160
exocyst complex component 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182473:
The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:116288001-116307233
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000021147 ENSMUSP00000021147
ENSMUST00000106413 ENSMUSP00000102021
ENSMUST00000106411 ENSMUSP00000102019
ENSMUST00000139699
ENSMUST00000141938
ENSMUST00000155288
ENSMUST00000136417
ENSMUST00000126731 ENSMUSP00000121794
ENSMUST00000133468 ENSMUSP00000121150
ENSMUST00000124281 ENSMUSP00000115737
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006887 exocytosis
GO:0008150 biological_process
GO:0015031 protein transport
Cellular Component
GO:0000145 exocyst
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0032584 growth cone membrane
GO:0034451 centriolar satellite
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000182473
View Gene Order
ENSBTAG00000007910
Not yet available
Pathways
NETPATH
REACTOME
REACT_209837
Membrane Trafficking pathway
REACT_247926
Metabolism of proteins pathway
REACT_206913
Peptide hormone metabolism pathway
REACT_207837
Insulin processing pathway
REACT_199054
Translocation of GLUT4 to the plasma membrane pathway
KEGG
mmu04910
Insulin signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15550
Insulin processing pathway
REACT_147867
Translocation of GLUT4 to the plasma membrane pathway
REACT_17015
Metabolism of proteins pathway
REACT_160078
Peptide hormone metabolism pathway
REACT_11123
Membrane Trafficking pathway
KEGG
hsa04910
Insulin signaling pathway pathway
INOH
PID NCI
cdc42_pathway
CDC42 signaling events
arf6_traffickingpathway
Arf6 trafficking events
insulin_pathway
Insulin Pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.470428
RefSeq NM_001162872 NM_016857 XM_006533735
OMIM
CCDS CCDS25664 CCDS48983
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca