InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Capza1

Summary

InnateDB Gene

IDBG-217524.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Capza1

Gene Name

capping protein (actin filament) muscle Z-line, alpha 1

Synonyms

Cappa1; CAPZ; CAZ1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000070372

Encoded Proteins

IDBP-268081

capping protein (actin filament) muscle Z-line, alpha 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116489:
CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. [provided by RefSeq, Jul 2008]
CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:104822779-104864505

Strand

Reverse strand

Band

F2.2

Transcripts

ENSMUST00000094028	ENSMUSP00000102381
ENSMUST00000155476

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Experimentally validated
Total	24 [view]
Protein-Protein	24 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding
GO:0051015	actin filament binding

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0051016	barbed-end actin filament capping

Cellular Component

GO:0005911	cell-cell junction
GO:0008290	F-actin capping protein complex
GO:0016020	membrane
GO:0030863	cortical cytoskeleton
GO:0070062	extracellular vesicular exosome
GO:0071203	WASH complex