Version 5.4
Homo sapiens Gene: ARID3B
Summary
InnateDB Gene IDBG-22221.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARID3B
Gene Name AT rich interactive domain 3B (BRIGHT-like)
Synonyms BDP; DRIL2
Species Homo sapiens
Ensembl Gene ENSG00000179361
Encoded Proteins
IDBP-22223
AT rich interactive domain 3B (BRIGHT-like)
IDBP-746850
IDBP-807134
AT rich interactive domain 3B (BRIGHT-like)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:74541177-74598131
Strand Forward strand
Band q24.1
Transcripts
ENST00000346246 ENSP00000343126
ENST00000563567
ENST00000566147 ENSP00000455668
ENST00000569680
ENST00000566468
ENST00000622429 ENSP00000477878
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001205 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000004661
View Gene Order
ENSBTAG00000011828
Not yet available
Cross-References
SwissProt
TrEMBL H3BQ92
UniProt Splice Variant
Entrez Gene 10620
UniGene
RefSeq NM_006465 XM_005254129
HUGO HGNC:14350
OMIM 612457
CCDS CCDS10264
HPRD
IMGT
EMBL AB208830 AC100835 AF116846 BC041792
GenPept AAD09133 AAH41792 BAD92067
RNA Seq Atlas 10620

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca