Homo sapiens Gene: GPR132
Summary
InnateDB Gene IDBG-22992.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR132
Gene Name G protein-coupled receptor 132
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000183484
Encoded Proteins
G protein-coupled receptor 132
G protein-coupled receptor 132
G protein-coupled receptor 132
G protein-coupled receptor 132
G protein-coupled receptor 132
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a subfamily member of the G-protein couple receptor (GPCR) superfamily. The encoded protein is a high-affinity receptor for lysophosphatidylcholine (LPC), a major phospholipid component of oxidized low density lipoprotein. This protein may react to LPC levels at sites of inflammation to limit the expansion of tissue-infiltrating cells. A similar protein in mouse is involved in cell cycle progression. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:105049389-105065445
Strand Reverse strand
Band q32.33
Transcripts
ENST00000329797 ENSP00000328818
ENST00000392585 ENSP00000376364
ENST00000551869 ENSP00000448513
ENST00000539291 ENSP00000438094
ENST00000546679
ENST00000549990 ENSP00000448776
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0006950 response to stress
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9UNW8
TrEMBL F8VRH8
UniProt Splice Variant
Entrez Gene 29933
UniGene Hs.532504
RefSeq NM_001278694 NM_001278695 NM_001278696 NM_013345
HUGO HGNC:17482
OMIM 606167
CCDS CCDS61567 CCDS9997
HPRD
IMGT
EMBL AB465599 AB465600 AF083955 AK292142 AK303654 AL512356 BC004555 BC084546 BT007257 CH471061 EU432121
GenPept AAD47380 AAH84546 AAP35921 ABY87920 BAF84831 BAG64656 BAG84609 BAG84610 EAW81898
RNA Seq Atlas 29933