Version 5.4
Homo sapiens Gene: SMTNL1
Summary
InnateDB Gene IDBG-231364.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMTNL1
Gene Name smoothelin-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000214872
Encoded Proteins
IDBP-231366
smoothelin-like 1
IDBP-585393
smoothelin-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SMTNL1, which is a member of the smoothelin (SMTN; MIM 602127) family, regulates contraction and relaxation of skeletal and smooth muscle fibers and mediates vascular adaptation to exercise (Wooldridge et al., 2008 [PubMed 18310078]).[supplied by OMIM, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:57542641-57550274
Strand Forward strand
Band q12.1
Transcripts
ENST00000399154 ENSP00000382108
ENST00000527972 ENSP00000432651
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0008157 protein phosphatase 1 binding
Biological Process
GO:0014823 response to activity
GO:0018105 peptidyl-serine phosphorylation
GO:0042493 response to drug
GO:0045907 positive regulation of vasoconstriction
GO:0045908 negative regulation of vasodilation
GO:0048644 muscle organ morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031430 M band
GO:0031674 I band
GO:0043292 contractile fiber
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027077
View Gene Order
ENSBTAG00000027524
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.68756
RefSeq NM_001105565 XM_005273819
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca