Version 5.4
Homo sapiens Gene: PLIN5
Summary
InnateDB Gene IDBG-233258.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLIN5
Gene Name perilipin 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000214456
Encoded Proteins
IDBP-19052
perilipin 5
IDBP-766115
IDBP-761392
IDBP-763758
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the perilipin family, such as PLIN5, coat intracellular lipid storage droplets and protect them from lipolytic degradation (Dalen et al., 2007 [PubMed 17234449]).[supplied by OMIM, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:4522531-4535224
Strand Reverse strand
Band p13.3
Transcripts
ENST00000381848 ENSP00000371272
ENST00000590350
ENST00000586133 ENSP00000468027
ENST00000589728
ENST00000588887 ENSP00000466255
ENST00000592610 ENSP00000464926
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0035473 lipase binding
GO:0042802 identical protein binding
Biological Process
GO:0010867 positive regulation of triglyceride biosynthetic process
GO:0010884 positive regulation of lipid storage
GO:0010890 positive regulation of sequestering of triglyceride
GO:0010897 negative regulation of triglyceride catabolic process
GO:0019915 lipid storage
GO:0031999 negative regulation of fatty acid beta-oxidation
GO:0032000 positive regulation of fatty acid beta-oxidation
GO:0034389 lipid particle organization
GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway
GO:0050995 negative regulation of lipid catabolic process
GO:0051646 mitochondrion localization
GO:0060192 negative regulation of lipase activity
GO:0060193 positive regulation of lipase activity
GO:2000378 negative regulation of reactive oxygen species metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005811 lipid particle
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000011305
View Gene Order
ENSBTAG00000038464
Not yet available
Cross-References
SwissProt
TrEMBL K7EIX1
UniProt Splice Variant
Entrez Gene 440503
UniGene Hs.131034
RefSeq NM_001013706
HUGO HGNC:33196
OMIM 613248
CCDS CCDS42473
HPRD
IMGT
EMBL AC011498
GenPept
RNA Seq Atlas 440503

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca