Version 5.4
Homo sapiens Gene: RNF180
Summary
InnateDB Gene IDBG-23596.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNF180
Gene Name ring finger protein 180
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164197
Encoded Proteins
IDBP-23598
ring finger protein 180
IDBP-23600
ring finger protein 180
IDBP-475505
ring finger protein 180
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:64165844-64372869
Strand Forward strand
Band q12.3
Transcripts
ENST00000389100 ENSP00000373752
ENST00000296615 ENSP00000296615
ENST00000504296 ENSP00000426884
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0031624 ubiquitin conjugating enzyme binding
GO:0046872 metal ion binding
Biological Process
GO:0000209 protein polyubiquitination
GO:0016567 protein ubiquitination
GO:0030534 adult behavior
GO:0031398 positive regulation of protein ubiquitination
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042415 norepinephrine metabolic process
GO:0042428 serotonin metabolic process
GO:0050790 regulation of catalytic activity
GO:1901360 organic cyclic compound metabolic process
Cellular Component
GO:0005635 nuclear envelope
GO:0016021 integral component of membrane
GO:0031227 intrinsic component of endoplasmic reticulum membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021720
View Gene Order
ENSBTAG00000043992
Not yet available
Cross-References
SwissProt Q86T96
TrEMBL D6RE88
UniProt Splice Variant
Entrez Gene 285671
UniGene Hs.657843
RefSeq NM_178532 NM_001113561 XM_006714589 XM_006714590
HUGO HGNC:27752
OMIM
CCDS CCDS34169 CCDS47219
HPRD 15263
IMGT
EMBL AC016623 AC092360 AK090756 AL832580 BC101277 BC101278 BC101279 BC101397
GenPept AAI01278 AAI01279 AAI01280 AAI01398 BAC03514 CAD89939
RNA Seq Atlas 285671

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca