Version 5.4
Homo sapiens Gene: HAUS7
Summary
InnateDB Gene IDBG-242765.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HAUS7
Gene Name HAUS augmin-like complex, subunit 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000213397
Encoded Proteins
IDBP-89438
HAUS augmin-like complex, subunit 7
IDBP-89440
HAUS augmin-like complex, subunit 7
IDBP-89442
HAUS augmin-like complex, subunit 7
IDBP-382716
HAUS augmin-like complex, subunit 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a subunit of the augmin complex, which regulates centrosome and mitotic spindle integrity, and is necessary for the completion of cytokinesis. The encoded protein was identified by interaction with ubiquitin C-terminal hydrolase 37. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome X:153447666-153495516
Strand Reverse strand
Band q28
Transcripts
ENST00000370212 ENSP00000359231
ENST00000370211 ENSP00000359230
ENST00000370210 ENSP00000359229
ENST00000435662 ENSP00000389431
ENST00000437046
ENST00000484394
ENST00000460898
ENST00000491286
ENST00000490165
ENST00000490453
ENST00000464993
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0031996 thioesterase binding
Biological Process
GO:0007067 mitotic nuclear division
GO:0051225 spindle assembly
GO:0051297 centrosome organization
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005819 spindle
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0070652 HAUS complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031371
View Gene Order
ENSBTAG00000014095
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.170835
RefSeq NM_017518 NM_080701
HUGO
OMIM
CCDS CCDS35438 CCDS35437
HPRD 18695
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca