Version 5.4
Homo sapiens Gene: ARPP21
Summary
InnateDB Gene IDBG-24449.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARPP21
Gene Name cAMP-regulated phosphoprotein, 21kDa
Synonyms ARPP-21; R3HDM3; RCS; TARPP
Species Homo sapiens
Ensembl Gene ENSG00000172995
Encoded Proteins
IDBP-24453
cAMP-regulated phosphoprotein, 21kDa
IDBP-237409
cAMP-regulated phosphoprotein, 21kDa
IDBP-237411
cAMP-regulated phosphoprotein, 21kDa
IDBP-370572
cAMP-regulated phosphoprotein, 21kDa
IDBP-370575
cAMP-regulated phosphoprotein, 21kDa
IDBP-370578
cAMP-regulated phosphoprotein, 21kDa
IDBP-370611
cAMP-regulated phosphoprotein, 21kDa
IDBP-370615
cAMP-regulated phosphoprotein, 21kDa
IDBP-370618
cAMP-regulated phosphoprotein, 21kDa
IDBP-370622
cAMP-regulated phosphoprotein, 21kDa
IDBP-370626
cAMP-regulated phosphoprotein, 21kDa
IDBP-370631
cAMP-regulated phosphoprotein, 21kDa
IDBP-370633
cAMP-regulated phosphoprotein, 21kDa
IDBP-370636
cAMP-regulated phosphoprotein, 21kDa
IDBP-370644
cAMP-regulated phosphoprotein, 21kDa
IDBP-370646
cAMP-regulated phosphoprotein, 21kDa
IDBP-370647
cAMP-regulated phosphoprotein, 21kDa
IDBP-370648
cAMP-regulated phosphoprotein, 21kDa
IDBP-370649
cAMP-regulated phosphoprotein, 21kDa
IDBP-370652
cAMP-regulated phosphoprotein, 21kDa
IDBP-370654
cAMP-regulated phosphoprotein, 21kDa
IDBP-370656
cAMP-regulated phosphoprotein, 21kDa
IDBP-370658
cAMP-regulated phosphoprotein, 21kDa
IDBP-370661
cAMP-regulated phosphoprotein, 21kDa
IDBP-370668
cAMP-regulated phosphoprotein, 21kDa
IDBP-473675
cAMP-regulated phosphoprotein, 21kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:35638945-35794496
Strand Forward strand
Band p22.3
Transcripts
ENST00000187397 ENSP00000187397
ENST00000396482 ENSP00000379742
ENST00000396481 ENSP00000379741
ENST00000450234 ENSP00000411644
ENST00000428373 ENSP00000412411
ENST00000421492 ENSP00000398598
ENST00000444190 ENSP00000405276
ENST00000449196 ENSP00000409808
ENST00000452563 ENSP00000396324
ENST00000438577 ENSP00000409331
ENST00000414496 ENSP00000415134
ENST00000419330 ENSP00000413005
ENST00000427542 ENSP00000401602
ENST00000412048 ENSP00000390151
ENST00000434383
ENST00000432682 ENSP00000389754
ENST00000432450 ENSP00000412341
ENST00000413378 ENSP00000390169
ENST00000417925 ENSP00000412326
ENST00000441454 ENSP00000406964
ENST00000436702 ENSP00000397720
ENST00000438071 ENSP00000410171
ENST00000446068 ENSP00000399482
ENST00000425289 ENSP00000408271
ENST00000427590 ENSP00000396116
ENST00000457165 ENSP00000412233
ENST00000474696 ENSP00000417838
ENST00000461826
ENST00000476327
ENST00000494494
ENST00000481854
ENST00000462173
ENST00000463970
ENST00000473138
ENST00000476052
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003676 nucleic acid binding
GO:0005516 calmodulin binding
Biological Process
GO:0008150 biological_process
GO:0034605 cellular response to heat
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032503
View Gene Order
ENSBTAG00000007732
Not yet available
Cross-References
SwissProt Q9UBL0
TrEMBL A8K1F3 C9J091 C9J2U3 C9J5R1 C9JD93 C9JI74 C9JQQ6 C9JTF2 C9JTX6 F8WDL2 H7C3J7
UniProt Splice Variant
Entrez Gene 10777
UniGene Hs.475902 Hs.602539
RefSeq NM_001025068 NM_001025069 NM_001267616 NM_001267617 NM_001267618 NM_001267619 NM_016300 NM_198399 XM_006712943 XM_006712944
HUGO HGNC:16968
OMIM 605488
CCDS CCDS2661 CCDS43063 CCDS58823 CCDS58824
HPRD
IMGT
EMBL AC016943 AC104308 AC133143 AF112220 AK055064 AK289868 AK294484 AL133109 BC017805 BC031106 BC036399 BC041385 BC051828 BC066651 CH471055
GenPept AAF17207 AAH17805 AAH31106 AAH36399 AAH41385 AAH51828 AAH66651 BAF82557 BAG51459 BAG57707 CAB61414 EAW64470 EAW64471 EAW64472
RNA Seq Atlas 10777

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca