Mus musculus Gene: Aoc2 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-267046.6 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | Aoc2 | ||||||||||||||||
Gene Name | amine oxidase, copper containing 2 (retina-specific) | ||||||||||||||||
Synonyms | |||||||||||||||||
Species | Mus musculus | ||||||||||||||||
Ensembl Gene | ENSMUSG00000078651 | ||||||||||||||||
Encoded Proteins |
amine oxidase, copper containing 2 (retina-specific)
amine oxidase, copper containing 2 (retina-specific)
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131480:
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 11:101325063-101329702 | ||||||||||||||||
Strand | Forward strand | ||||||||||||||||
Band | D | ||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME | |||||||||||||||||
KEGG |
beta-Alanine metabolism pathway
Tyrosine metabolism pathway
Glycine, serine and threonine metabolism pathway
Phenylalanine metabolism pathway
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INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME | |||||||||||||||||
KEGG |
Phenylalanine metabolism pathway
Glycine, serine and threonine metabolism pathway
Tyrosine metabolism pathway
beta-Alanine metabolism pathway
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INOH |
Tryptophan degradation pathway
Phenylalanine degradation pathway
Arginine Proline metabolism pathway
Tyrosine metabolism pathway
Glycine Serine metabolism pathway
Histidine degradation pathway
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PID NCI | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | Q812C9 | ||||||||||||||||
TrEMBL | A2A4I9 | ||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 237940 | ||||||||||||||||
UniGene | Mm.302277 | ||||||||||||||||
RefSeq | NM_178932 XM_006533247 | ||||||||||||||||
OMIM | |||||||||||||||||
CCDS | CCDS25464 | ||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
MGI ID | MGI:2668431 | ||||||||||||||||
MGI Symbol | Aoc2 | ||||||||||||||||
EMBL | AF350445 AF350446 AL590969 BC150843 BC150848 | ||||||||||||||||
GenPept | AAI50844 AAI50849 AAK58864 AAK58865 CAM19554 | ||||||||||||||||
RNA Seq Atlas | 237940 | ||||||||||||||||