Version 5.4
| Mus musculus Gene: Dohh | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-271119.4 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Dohh | ||||||||||
| Gene Name | deoxyhypusine hydroxylase/monooxygenase | ||||||||||
| Synonyms | 1110033C18Rik; AI585913; AL022869; Hlrc1 | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000078440 | ||||||||||
| Encoded Proteins |
deoxyhypusine hydroxylase/monooxygenase
deoxyhypusine hydroxylase/monooxygenase
deoxyhypusine hydroxylase/monooxygenase
deoxyhypusine hydroxylase/monooxygenase
deoxyhypusine hydroxylase/monooxygenase
deoxyhypusine hydroxylase/monooxygenase
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| Protein Structure | |||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129932:
This gene encodes a metalloenzyme that catalyzes the last step in the conversion of lysine to the unique amino acid hypusine in eukaryotic initiation factor 5A. The encoded protein hydroxylates deoxyhypusine to form hypusine in the mature eukaryotic initiation factor 5A protein. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 10:81384428-81391560 | ||||||||||
| Strand | Forward strand | ||||||||||
| Band | C1 | ||||||||||
| Transcripts | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Metabolism of proteins pathway
Post-translational protein modification pathway
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
Hypusine synthesis from eIF5A-lysine pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Hypusine synthesis from eIF5A-lysine pathway
Post-translational protein modification pathway
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
Metabolism of proteins pathway
Hypusine synthesis from eIF5A-lysine pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | |||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | |||||||||||
| UniGene | Mm.294975 Mm.415976 Mm.485349 | ||||||||||
| RefSeq | NM_133964 XM_006514356 XM_006542830 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS35997 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | |||||||||||
| MGI Symbol | |||||||||||
| EMBL | |||||||||||
| GenPept | |||||||||||
| RNA Seq Atlas | |||||||||||