Version 5.4
Homo sapiens Gene: FNIP1
Summary
InnateDB Gene IDBG-281600.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FNIP1
Gene Name folliculin interacting protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000217128
Encoded Proteins
IDBP-40476
folliculin interacting protein 1
IDBP-40480
folliculin interacting protein 1
IDBP-484190
folliculin interacting protein 1
IDBP-479699
folliculin interacting protein 1
IDBP-475072
folliculin interacting protein 1
IDBP-813564
folliculin interacting protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:131641714-131797063
Strand Reverse strand
Band q31.1
Transcripts
ENST00000307954 ENSP00000310453
ENST00000307968 ENSP00000309266
ENST00000514667 ENSP00000426948
ENST00000510461 ENSP00000421985
ENST00000511848 ENSP00000425619
ENST00000623690
ENST00000615660 ENSP00000480650
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001932 regulation of protein phosphorylation
GO:0001934 positive regulation of protein phosphorylation
GO:0002327 immature B cell differentiation
GO:0002904 positive regulation of B cell apoptotic process
GO:0009267 cellular response to starvation
GO:0031929 TOR signaling
GO:0032007 negative regulation of TOR signaling
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:2000973 regulation of pro-B cell differentiation
Cellular Component
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q8TF40
TrEMBL B3KX44
UniProt Splice Variant
Entrez Gene 96459
UniGene Hs.591273
RefSeq NM_001008738 NM_133372
HUGO HGNC:29418
OMIM 610594
CCDS CCDS34226 CCDS34227
HPRD 17233
IMGT
EMBL AB075841 AC004227 AC004622 AC005593 AC008497 AC008695 AC026754 AK126675 AL832008 BC001956 DQ145719
GenPept AAH01956 AAZ65854 BAB85547 BAG54356 CAD91145
RNA Seq Atlas 96459

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca