Version 5.4
Homo sapiens Gene: SLC26A7
Summary
InnateDB Gene IDBG-28311.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC26A7
Gene Name solute carrier family 26, member 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147606
Encoded Proteins
IDBP-28315
solute carrier family 26, member 7
IDBP-28317
solute carrier family 26, member 7
IDBP-473615
solute carrier family 26, member 7
IDBP-476542
solute carrier family 26, member 7
IDBP-477268
solute carrier family 26, member 7
IDBP-483263
solute carrier family 26, member 7
IDBP-807742
solute carrier family 26 (anion exchanger), member 7
IDBP-807757
solute carrier family 26 (anion exchanger), member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. This gene has abundant and specific expression in the kidney. Splice variants that use both alternate transcription initiation and polyadenylation sites have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:91209494-91398152
Strand Forward strand
Band q21.3
Transcripts
ENST00000276609 ENSP00000276609
ENST00000309536 ENSP00000309504
ENST00000522181 ENSP00000427712
ENST00000522862 ENSP00000428881
ENST00000523719 ENSP00000428849
ENST00000520818 ENSP00000428747
ENST00000520249
ENST00000517930
ENST00000617233 ENSP00000482549
ENST00000617078 ENSP00000482686
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005253 anion channel activity
GO:0005254 chloride channel activity
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015116 sulfate transmembrane transporter activity
GO:0015301 anion:anion antiporter activity
GO:0019531 oxalate transmembrane transporter activity
Biological Process
GO:0001696 gastric acid secretion
GO:0006811 ion transport
GO:0006820 anion transport
GO:0006821 chloride transport
GO:0008272 sulfate transport
GO:0015701 bicarbonate transport
GO:0019532 oxalate transport
GO:0055085 transmembrane transport
GO:1902358 sulfate transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0055038 recycling endosome membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040569
View Gene Order
ENSBTAG00000032301
Not yet available
Pathways
NETPATH
REACTOME
REACT_19357
Multifunctional anion exchangers pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
hsa04971
Gastric acid secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 115111
UniGene
RefSeq NM_001282357 NM_001282356 NM_052832 NM_134266
HUGO HGNC:14467
OMIM 608479
CCDS CCDS75765 CCDS6254 CCDS6255
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 115111

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca