Version 5.4
Homo sapiens Gene: GAL3ST4
Summary
InnateDB Gene IDBG-30821.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GAL3ST4
Gene Name galactose-3-O-sulfotransferase 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000197093
Encoded Proteins
IDBP-30823
galactose-3-O-sulfotransferase 4
IDBP-383299
galactose-3-O-sulfotransferase 4
IDBP-383301
galactose-3-O-sulfotransferase 4
IDBP-383302
galactose-3-O-sulfotransferase 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate to the C-3' position of galactose residues in O-linked glycoproteins. This enzyme is highly specific for core 1 structures, with asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc being good substrates. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:100159244-100168750
Strand Reverse strand
Band q22.1
Transcripts
ENST00000360039 ENSP00000353142
ENST00000413800 ENSP00000400451
ENST00000423751 ENSP00000399066
ENST00000411994 ENSP00000414733
ENST00000495882
ENST00000498000
ENST00000482469
ENST00000460995
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001733 galactosylceramide sulfotransferase activity
GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding
GO:0050694 galactose 3-O-sulfotransferase activity
GO:0050698 proteoglycan sulfotransferase activity
Biological Process
GO:0006790 sulfur compound metabolic process
GO:0007267 cell-cell signaling
GO:0009058 biosynthetic process
GO:0009100 glycoprotein metabolic process
GO:0009311 oligosaccharide metabolic process
GO:0030166 proteoglycan biosynthetic process
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000075593
View Gene Order
ENSBTAG00000015017
Not yet available
Cross-References
SwissProt
TrEMBL C9IZ77
UniProt Splice Variant
Entrez Gene 79690
UniGene Hs.44856
RefSeq NM_024637
HUGO HGNC:24145
OMIM 608235
CCDS CCDS5688
HPRD 12195
IMGT
EMBL AC073842
GenPept
RNA Seq Atlas 79690

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca