Version 5.4
Homo sapiens Gene: RIMS2
Summary
InnateDB Gene IDBG-31870.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RIMS2
Gene Name regulating synaptic membrane exocytosis 2
Synonyms OBOE; RAB3IP3; RIM2
Species Homo sapiens
Ensembl Gene ENSG00000176406
Encoded Proteins
IDBP-31876
regulating synaptic membrane exocytosis 2
IDBP-31884
regulating synaptic membrane exocytosis 2
IDBP-295574
regulating synaptic membrane exocytosis 2
IDBP-295569
regulating synaptic membrane exocytosis 2
IDBP-374790
regulating synaptic membrane exocytosis 2
IDBP-477698
regulating synaptic membrane exocytosis 2
IDBP-481243
regulating synaptic membrane exocytosis 2
IDBP-482611
regulating synaptic membrane exocytosis 2
IDBP-474597
regulating synaptic membrane exocytosis 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:103500748-104256094
Strand Forward strand
Band q22.3
Transcripts
ENST00000262231 ENSP00000262231
ENST00000339750 ENSP00000342051
ENST00000395361
ENST00000406091 ENSP00000384892
ENST00000408894 ENSP00000386228
ENST00000436393 ENSP00000390665
ENST00000504942 ENSP00000427018
ENST00000515551 ENSP00000425205
ENST00000507740 ENSP00000423559
ENST00000522174
ENST00000507677
ENST00000512598
ENST00000501515
ENST00000511046
ENST00000523362 ENSP00000428478
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017137 Rab GTPase binding
GO:0019904 protein domain specific binding
GO:0044325 ion channel binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006886 intracellular protein transport
GO:0017156 calcium ion-dependent exocytosis
GO:0017157 regulation of exocytosis
GO:0019933 cAMP-mediated signaling
GO:0030073 insulin secretion
GO:0042391 regulation of membrane potential
GO:0048791 calcium ion-dependent exocytosis of neurotransmitter
Cellular Component
GO:0030054 cell junction
GO:0042734 presynaptic membrane
GO:0043234 protein complex
GO:0045202 synapse
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037386
View Gene Order
ENSBTAG00000003827
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.129407 Hs.596511 Hs.655271
RefSeq NM_001282881 NM_001282882 NM_014677 XM_006716694 XM_006716698
HUGO
OMIM
CCDS CCDS43761 CCDS64948 CCDS64949
HPRD 09436
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca