Version 5.4
Homo sapiens Gene: TFIP11
Summary
InnateDB Gene IDBG-3198.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFIP11
Gene Name tuftelin interacting protein 11
Synonyms bK445C9.6; hNtr1; NTR1; Spp382; TIP39
Species Homo sapiens
Ensembl Gene ENSG00000100109
Encoded Proteins
IDBP-294876
tuftelin interacting protein 11
IDBP-294875
tuftelin interacting protein 11
IDBP-294869
tuftelin interacting protein 11
IDBP-294872
tuftelin interacting protein 11
IDBP-368850
tuftelin interacting protein 11
IDBP-368856
tuftelin interacting protein 11
IDBP-368861
tuftelin interacting protein 11
IDBP-368864
tuftelin interacting protein 11
IDBP-368867
tuftelin interacting protein 11
IDBP-807052
tuftelin interacting protein 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary TFIP11 is a nuclear speckle-localized protein that may play a role in spliceosome disassembly in Cajal bodies (Stanek et al., 2008 [PubMed 18367544]).[supplied by OMIM, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:26491225-26512505
Strand Reverse strand
Band q12.1
Transcripts
ENST00000407690 ENSP00000384421
ENST00000407431 ENSP00000383892
ENST00000407148 ENSP00000385861
ENST00000405938 ENSP00000384297
ENST00000450493 ENSP00000394266
ENST00000455080 ENSP00000399347
ENST00000418876 ENSP00000404973
ENST00000420242 ENSP00000397475
ENST00000440258 ENSP00000411840
ENST00000492137
ENST00000481357
ENST00000496523
ENST00000493698
ENST00000479489
ENST00000472918
ENST00000464449
ENST00000619735 ENSP00000480171
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 32 [view]
Protein-Protein 31 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0000390 spliceosomal complex disassembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006355 regulation of transcription, DNA-templated
GO:0006396 RNA processing
GO:0031214 biomineral tissue development
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
GO:0016607 nuclear speck
GO:0071008 U2-type post-mRNA release spliceosomal complex
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029345
View Gene Order
ENSBTAG00000012288
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.20225
RefSeq NM_001008697 NM_012143
HUGO
OMIM
CCDS CCDS13838
HPRD 11628
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca