Version 5.4
Homo sapiens Gene: FAIM2
Summary
InnateDB Gene IDBG-32034.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAIM2
Gene Name Fas apoptotic inhibitory molecule 2
Synonyms LFG; LFG2; NGP35; NMP35; TMBIM2
Species Homo sapiens
Ensembl Gene ENSG00000135472
Encoded Proteins
IDBP-32036
Fas apoptotic inhibitory molecule 2
IDBP-589328
Fas apoptotic inhibitory molecule 2
IDBP-599063
Fas apoptotic inhibitory molecule 2
IDBP-603048
Fas apoptotic inhibitory molecule 2
IDBP-598245
Fas apoptotic inhibitory molecule 2
IDBP-590249
Fas apoptotic inhibitory molecule 2
IDBP-600282
Fas apoptotic inhibitory molecule 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:49866896-49904217
Strand Reverse strand
Band q13.12
Transcripts
ENST00000320634 ENSP00000321951
ENST00000550890 ENSP00000450132
ENST00000550195 ENSP00000447715
ENST00000550635 ENSP00000449711
ENST00000552669 ENSP00000446771
ENST00000552863 ENSP00000449957
ENST00000547871 ENSP00000449360
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0002931 response to ischemia
GO:0006915 apoptotic process
GO:0021549 cerebellum development
GO:0021680 cerebellar Purkinje cell layer development
GO:0021681 cerebellar granular layer development
GO:0021702 cerebellar Purkinje cell differentiation
GO:0043066 negative regulation of apoptotic process
GO:0043523 regulation of neuron apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:2001234 negative regulation of apoptotic signaling pathway
Cellular Component
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0045121 membrane raft
GO:0045211 postsynaptic membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000023011
View Gene Order
ENSBTAG00000017504
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
faspathway
FAS (CD95) signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 23017
UniGene Hs.567424
RefSeq NM_012306 XM_005268730
HUGO HGNC:17067
OMIM 604306
CCDS CCDS8791
HPRD 09184
IMGT
EMBL
GenPept
RNA Seq Atlas 23017

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca