Version 5.4
Homo sapiens Gene: SYDE1
Summary
InnateDB Gene IDBG-34192.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYDE1
Gene Name synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000105137
Encoded Proteins
IDBP-34194
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
IDBP-765964
IDBP-763806
IDBP-759806
IDBP-765911
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:15107403-15114988
Strand Forward strand
Band p13.12
Transcripts
ENST00000342784 ENSP00000341489
ENST00000597977 ENSP00000473151
ENST00000600252 ENSP00000469489
ENST00000600440 ENSP00000470733
ENST00000602203 ENSP00000471553
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005100 Rho GTPase activator activity
GO:0005515 protein binding
GO:0032403 protein complex binding
Biological Process
GO:0007130 synaptonemal complex assembly
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0016081 synaptic vesicle docking involved in exocytosis
GO:0032862 activation of Rho GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0050806 positive regulation of synaptic transmission
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
GO:0044300 cerebellar mossy fiber
GO:0097060 synaptic membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032714
View Gene Order
ENSBTAG00000015184
Not yet available
Pathways
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q6ZW31
TrEMBL M0QXZ8 M0R3D3
UniProt Splice Variant
Entrez Gene 85360
UniGene Hs.528701 Hs.732011
RefSeq NM_001300910 NM_033025 XM_005260126
HUGO HGNC:25824
OMIM
CCDS CCDS12324 CCDS74299
HPRD
IMGT
EMBL AC004794 AK023573 AK123686 BC018942 BC029926 CH471106
GenPept AAH18942 AAH29926 BAB14612 BAC85676 EAW84461 EAW84462 EAW84463
RNA Seq Atlas 85360

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca