Version 5.4
Homo sapiens Gene: ZNF385A
Summary
InnateDB Gene IDBG-37861.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF385A
Gene Name zinc finger protein 385A
Synonyms HZF; RZF; ZFP385; ZNF385
Species Homo sapiens
Ensembl Gene ENSG00000161642
Encoded Proteins
IDBP-37863
zinc finger protein 385A
IDBP-37865
zinc finger protein 385A
IDBP-241851
zinc finger protein 385A
IDBP-597597
zinc finger protein 385A
IDBP-598570
zinc finger protein 385A
IDBP-594981
zinc finger protein 385A
IDBP-602377
zinc finger protein 385A
IDBP-591418
zinc finger protein 385A
IDBP-585431
zinc finger protein 385A
IDBP-596783
zinc finger protein 385A
IDBP-603710
zinc finger protein 385A
IDBP-598360
zinc finger protein 385A
IDBP-583664
zinc finger protein 385A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Zinc finger proteins, such as ZNF385A, are regulatory proteins that act as transcription factors, bind single- or double-stranded RNA, or interact with other proteins (Sharma et al., 2004 [PubMed 15527981]).[supplied by OMIM, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:54369133-54391298
Strand Reverse strand
Band q13.13
Transcripts
ENST00000338010 ENSP00000338927
ENST00000352268 ENSP00000293385
ENST00000394313 ENSP00000377849
ENST00000551109 ENSP00000449161
ENST00000550779 ENSP00000450373
ENST00000546970 ENSP00000446913
ENST00000552382
ENST00000551771 ENSP00000447162
ENST00000546919 ENSP00000448466
ENST00000549937 ENSP00000448567
ENST00000549962 ENSP00000450149
ENST00000547210 ENSP00000448264
ENST00000550774 ENSP00000449462
ENST00000550120 ENSP00000448754
ENST00000551864
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007599 hemostasis
GO:0007611 learning or memory
GO:0007626 locomotory behavior
GO:0008298 intracellular mRNA localization
GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression
GO:0030220 platelet formation
GO:0035855 megakaryocyte development
GO:0045600 positive regulation of fat cell differentiation
GO:0070889 platelet alpha granule organization
GO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2000765 regulation of cytoplasmic translation
Cellular Component
GO:0000790 nuclear chromatin
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0030425 dendrite
GO:0043025 neuronal cell body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000000552
View Gene Order
ENSBTAG00000015604
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
Cross-References
SwissProt Q96PM9
TrEMBL
UniProt Splice Variant
Entrez Gene 25946
UniGene Hs.505653
RefSeq NM_001130967 NM_001130968 NM_001290001 NM_001290002 NM_001290004 NM_015481 XM_005268783 XM_005268785 XM_006719342
HUGO HGNC:17521
OMIM 609124
CCDS CCDS44910 CCDS44911 CCDS8879
HPRD 16448
IMGT
EMBL AB593085 AC078778 AC079313 AF304052 AK024404 AK296564 AK315613 AL117462 AY461717 BC029752 CH471054 CR457327
GenPept AAH29752 AAL08625 AAS19275 BAB14910 BAG37982 BAG59184 BAJ84025 CAB55938 CAG33608 EAW96777
RNA Seq Atlas 25946

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca