Version 5.4
Homo sapiens Gene: RAB5B
Summary
InnateDB Gene IDBG-39641.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAB5B
Gene Name RAB5B, member RAS oncogene family
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000111540
Encoded Proteins
IDBP-39643
RAB5B, member RAS oncogene family
IDBP-377451
RAB5B, member RAS oncogene family
IDBP-592369
RAB5B, member RAS oncogene family
IDBP-587250
RAB5B, member RAS oncogene family
IDBP-584362
RAB5B, member RAS oncogene family
IDBP-586051
RAB5B, member RAS oncogene family
IDBP-602229
RAB5B, member RAS oncogene family
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:55973913-55996683
Strand Forward strand
Band q13.2
Transcripts
ENST00000360299 ENSP00000353444
ENST00000448789 ENSP00000391319
ENST00000553116 ENSP00000450168
ENST00000549505 ENSP00000450285
ENST00000546810
ENST00000548068 ENSP00000447895
ENST00000549915 ENSP00000449762
ENST00000551459 ENSP00000449554
ENST00000549034
ENST00000550283
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
GO:0030742 GTP-dependent protein binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007032 endosome organization
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0019882 antigen processing and presentation
GO:0030100 regulation of endocytosis
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030139 endocytic vesicle
GO:0031901 early endosome membrane
GO:0042470 melanosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000000711
View Gene Order
ENSBTAG00000014129
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
hsa04962
Vasopressin-regulated water reabsorption pathway
hsa05146
Amoebiasis pathway
hsa04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F8VUA5 F8VVZ0
UniProt Splice Variant
Entrez Gene 5869
UniGene Hs.157659 Hs.595565 Hs.702025 Hs.703790
RefSeq NM_001252036 NM_001252037 NM_002868 XM_005269051 XM_005269052 XM_006719540
HUGO HGNC:9784
OMIM 179514
CCDS CCDS58244 CCDS8900
HPRD 01544
IMGT
EMBL AC034102
GenPept
RNA Seq Atlas 102723609 5869

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca