Version 5.4
Homo sapiens Gene: CALU
Summary
InnateDB Gene IDBG-39925.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CALU
Gene Name calumenin
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000128595
Encoded Proteins
IDBP-39929
calumenin
IDBP-386128
calumenin
IDBP-478039
calumenin
IDBP-475972
calumenin
IDBP-592154
calumenin
IDBP-593845
calumenin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:128739292-128771807
Strand Forward strand
Band q32.1
Transcripts
ENST00000249364 ENSP00000249364
ENST00000449187 ENSP00000408838
ENST00000479257 ENSP00000420381
ENST00000493278 ENSP00000417973
ENST00000542996 ENSP00000438248
ENST00000535011 ENSP00000442110
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 85 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 85 [view]
Protein-Protein 84 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0002576 platelet degranulation
GO:0007596 blood coagulation
GO:0008150 biological_process
GO:0030168 platelet activation
Cellular Component
GO:0005576 extracellular region
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0033018 sarcoplasmic reticulum lumen
GO:0042470 melanosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029767
View Gene Order
ENSBTAG00000016481
Not yet available
Pathways
NETPATH
REACTOME
REACT_318
Platelet degranulation pathway
REACT_1280
Response to elevated platelet cytosolic Ca2+ pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.624418 Hs.735529 Hs.743262 Hs.7753
RefSeq NM_001130674 NM_001199671 NM_001199672 NM_001199673 NM_001219
HUGO
OMIM
CCDS CCDS47703 CCDS56506 CCDS56507 CCDS56508 CCDS5805
HPRD 04569
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca