InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: OPN1SW

Summary

InnateDB Gene

IDBG-39986.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

OPN1SW

Gene Name

opsin 1 (cone pigments), short-wave-sensitive

Synonyms

BCP; BOP; CBT

Species

Homo sapiens

Ensembl Gene

ENSG00000128617

Encoded Proteins

IDBP-39988

opsin 1 (cone pigments), short-wave-sensitive

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene belongs to the G-protein coupled receptor 1 family, opsin subfamily. It encodes the blue cone pigment gene which is one of three types of cone photoreceptors responsible for normal color vision. Defects in this gene are the cause of tritan color blindness (tritanopia). Affected individuals lack blue and yellow sensory mechanisms while retaining those for red and green. Defective blue vision is characteristic. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:128772491-128775790

Strand

Reverse strand

Band

q32.1

Transcripts

ENST00000249389

ENSP00000249389

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0009881	photoreceptor activity

Biological Process

GO:0001523	retinoid metabolic process
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007601	visual perception
GO:0007602	phototransduction
GO:0007603	phototransduction, visible light
GO:0018298	protein-chromophore linkage

Cellular Component

GO:0001750	photoreceptor outer segment
GO:0005887	integral component of plasma membrane
GO:0016021	integral component of membrane
GO:0042622	photoreceptor outer segment membrane