Version 5.4
Homo sapiens Gene: SMCHD1
Summary
InnateDB Gene IDBG-402.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMCHD1
Gene Name structural maintenance of chromosomes flexible hinge domain containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000101596
Encoded Proteins
IDBP-396
structural maintenance of chromosomes flexible hinge domain containing 1
IDBP-727708
IDBP-726095
IDBP-727294
IDBP-727822
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein which contains a hinge region domain found in members of the SMC (structural maintenance of chromosomes) protein family. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:2655738-2805017
Strand Forward strand
Band p11.32
Transcripts
ENST00000320876 ENSP00000326603
ENST00000577300
ENST00000584897 ENSP00000464684
ENST00000581383
ENST00000581711
ENST00000581631
ENST00000585229 ENSP00000462050
ENST00000583441
ENST00000583800 ENSP00000463036
ENST00000577880 ENSP00000463049
ENST00000581226
ENST00000583344
ENST00000609587
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0009048 dosage compensation by inactivation of X chromosome
GO:0051276 chromosome organization
GO:0060821 inactivation of X chromosome by DNA methylation
Cellular Component
GO:0001740 Barr body
GO:0005694 chromosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024054
View Gene Order
ENSBTAG00000003354
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.596122 Hs.607245 Hs.607656 Hs.8118
RefSeq NM_015295 XM_005258102 XM_006722321
HUGO
OMIM
CCDS CCDS45822
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca