Version 5.4
Homo sapiens Gene: APOF
Summary
InnateDB Gene IDBG-40996.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOF
Gene Name apolipoprotein F
Synonyms Apo-F; LTIP
Species Homo sapiens
Ensembl Gene ENSG00000175336
Encoded Proteins
IDBP-233694
apolipoprotein F
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene is one of the minor apolipoproteins found in plasma. This protein forms complexes with lipoproteins and may be involved in transport and/or esterification of cholesterol. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:56360569-56362823
Strand Reverse strand
Band q13.3
Transcripts
ENST00000398189 ENSP00000381250
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005319 lipid transporter activity
GO:0015485 cholesterol binding
Biological Process
GO:0006629 lipid metabolic process
GO:0006641 triglyceride metabolic process
GO:0006869 lipid transport
GO:0008203 cholesterol metabolic process
GO:0033344 cholesterol efflux
Cellular Component
GO:0005576 extracellular region
GO:0034362 low-density lipoprotein particle
GO:0034364 high-density lipoprotein particle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000047631
View Gene Order
ENSBTAG00000004384
Not yet available
Pathways
NETPATH
REACTOME
REACT_6934
LDL-mediated lipid transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_267716
Orphan transporters pathway
REACT_6823
Lipoprotein metabolism pathway
REACT_111217
Metabolism pathway
REACT_602
Lipid digestion, mobilization, and transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q13790
TrEMBL F5GXS5
UniProt Splice Variant
Entrez Gene 319
UniGene Hs.534302
RefSeq NM_001638
HUGO HGNC:615
OMIM 107760
CCDS CCDS44923
HPRD
IMGT
EMBL AC025574 BC026257 L27050
GenPept AAA65642 AAH26257
RNA Seq Atlas 319

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca