Version 5.4
Homo sapiens Gene: PLB1
Summary
InnateDB Gene IDBG-41280.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLB1
Gene Name phospholipase B1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000163803
Encoded Proteins
IDBP-41282
phospholipase B1
IDBP-294317
phospholipase B1
IDBP-370714
phospholipase B1
IDBP-370795
phospholipase B1
IDBP-370800
phospholipase B1
IDBP-370807
phospholipase B1
IDBP-370810
phospholipase B1
IDBP-370811
phospholipase B1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:28457145-28643788
Strand Forward strand
Band p23.2
Transcripts
ENST00000327757 ENSP00000330442
ENST00000404858 ENSP00000384187
ENST00000416713 ENSP00000407076
ENST00000422425 ENSP00000416440
ENST00000436544 ENSP00000392493
ENST00000411743 ENSP00000404723
ENST00000444257 ENSP00000391810
ENST00000436775 ENSP00000399712
ENST00000485642
ENST00000481449
ENST00000479065
ENST00000473272
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004622 lysophospholipase activity
GO:0004623 phospholipase A2 activity
GO:0016298 lipase activity
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0001523 retinoid metabolic process
GO:0006629 lipid metabolic process
GO:0006644 phospholipid metabolic process
GO:0007603 phototransduction, visible light
GO:0016042 lipid catabolic process
GO:0036151 phosphatidylcholine acyl-chain remodeling
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029134
View Gene Order
ENSBTAG00000018669
Not yet available
Pathways
NETPATH
REACTOME
REACT_24968
Retinoid metabolism and transport pathway
REACT_120829
Acyl chain remodelling of PC pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_111102
Signal Transduction pathway
REACT_160102
Diseases associated with visual transduction pathway
REACT_120870
Phospholipid metabolism pathway
REACT_160125
Visual phototransduction pathway
REACT_111217
Metabolism pathway
REACT_116125
Disease pathway
KEGG
hsa00592
alpha-Linolenic acid metabolism pathway
hsa00590
Arachidonic acid metabolism pathway
hsa00564
Glycerophospholipid metabolism pathway
hsa00591
Linoleic acid metabolism pathway
hsa00565
Ether lipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.444933
RefSeq NM_001170585 NM_153021
HUGO
OMIM
CCDS CCDS33168 CCDS54340
HPRD 15141
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca