Version 5.4
Homo sapiens Gene: RFWD3
Summary
InnateDB Gene IDBG-42109.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RFWD3
Gene Name ring finger and WD repeat domain 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000168411
Encoded Proteins
IDBP-42111
ring finger and WD repeat domain 3
IDBP-747396
IDBP-751983
IDBP-749473
IDBP-752883
IDBP-751535
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:74621394-74666881
Strand Reverse strand
Band q23.1
Transcripts
ENST00000361070 ENSP00000354361
ENST00000575397
ENST00000572840
ENST00000572337 ENSP00000459465
ENST00000571776
ENST00000575281
ENST00000575154
ENST00000576652 ENSP00000459515
ENST00000575113 ENSP00000461285
ENST00000572990 ENSP00000459899
ENST00000572610
ENST00000571750 ENSP00000460049
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
GO:0097371 MDM2/MDM4 family protein binding
Biological Process
GO:0006281 DNA repair
GO:0010212 response to ionizing radiation
GO:0016567 protein ubiquitination
GO:0031571 mitotic G1 DNA damage checkpoint
GO:2000001 regulation of DNA damage checkpoint
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016605 PML body
GO:0035861 site of double-strand break
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033596
View Gene Order
ENSBTAG00000004460
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.567525
RefSeq NM_018124 XM_005256021 XM_005256022 XM_006721227
HUGO
OMIM
CCDS CCDS32486
HPRD 07678
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca