Version 5.4
Homo sapiens Gene: ATRN
Summary
InnateDB Gene IDBG-46868.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATRN
Gene Name attractin
Synonyms DPPT-L; MGCA
Species Homo sapiens
Ensembl Gene ENSG00000088812
Encoded Proteins
IDBP-46870
attractin
IDBP-363921
attractin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other two isoforms are secreted proteins involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:3471040-3651122
Strand Forward strand
Band p13
Transcripts
ENST00000262919 ENSP00000262919
ENST00000446916 ENSP00000416587
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0006954 inflammatory response
GO:0006979 response to oxidative stress
GO:0007275 multicellular organismal development
GO:0021549 cerebellum development
GO:0040014 regulation of multicellular organism growth
GO:0042552 myelination
GO:0043473 pigmentation
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027312
View Gene Order
ENSBTAG00000003848
Not yet available
Cross-References
SwissProt O75882
TrEMBL
UniProt Splice Variant
Entrez Gene 8455
UniGene Hs.276252 Hs.705193
RefSeq NM_001207047 NM_139322 NM_139321 XM_005260860 XM_005260861
HUGO HGNC:885
OMIM 603130
CCDS CCDS13054 CCDS13053
HPRD 04388
IMGT
EMBL AB011120 AF106861 AF218889 AF218890 AF218891 AF218892 AF218893 AF218894 AF218895 AF218896 AF218897 AF218898 AF218899 AF218900 AF218901 AF218902 AF218903 AF218904 AF218905 AF218906 AF218907 AF218908 AF218909 AF218910 AF218911 AF218912 AF218913 AF218914 AF218915 AK293010 AL109805 AL132773 AL353193 BC101705
GenPept AAD03057 AAF72881 AAF72882 AAI01706 BAA25474 BAF85699 CAH70471 CAH70472 CAI21876 CAI21878 CAI22614 CAI22616
RNA Seq Atlas 8455

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca