InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: SH3GL2

Summary

InnateDB Gene

IDBG-51983.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SH3GL2

Gene Name

SH3-domain GRB2-like 2

Synonyms

CNSA2; EEN-B1; SH3D2A; SH3P4

Species

Homo sapiens

Ensembl Gene

ENSG00000107295

Encoded Proteins

IDBP-51985

SH3-domain GRB2-like 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:17579082-17797129

Strand

Forward strand

Band

p22.2

Transcripts

ENST00000380607	ENSP00000369981
ENST00000467085

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 112 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	112 [view]
Protein-Protein	112 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008289	lipid binding
GO:0042802	identical protein binding

Biological Process

GO:0002090	regulation of receptor internalization
GO:0006892	post-Golgi vesicle-mediated transport
GO:0007165	signal transduction
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0007411	axon guidance
GO:0007417	central nervous system development
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
GO:0048011	neurotrophin TRK receptor signaling pathway
GO:0048488	synaptic vesicle endocytosis
GO:0061024	membrane organization

Cellular Component

GO:0000139	Golgi membrane
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0030669	clathrin-coated endocytic vesicle membrane
GO:0070062	extracellular vesicular exosome