Version 5.4
Homo sapiens Gene: DCTN4
Summary
InnateDB Gene IDBG-53953.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DCTN4
Gene Name dynactin 4 (p62)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132912
Encoded Proteins
IDBP-380263
dynactin 4 (p62)
IDBP-380265
dynactin 4 (p62)
IDBP-380274
dynactin 4 (p62)
IDBP-476007
dynactin 4 (p62)
IDBP-473464
dynactin 4 (p62)
IDBP-481780
dynactin 4 (p62)
IDBP-482290
dynactin 4 (p62)
IDBP-475526
dynactin 4 (p62)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:150708440-150759109
Strand Reverse strand
Band q33.1
Transcripts
ENST00000446090 ENSP00000414906
ENST00000447998 ENSP00000416968
ENST00000424236 ENSP00000411251
ENST00000518909
ENST00000522625
ENST00000521728 ENSP00000428987
ENST00000519552
ENST00000519313
ENST00000518015 ENSP00000430993
ENST00000521448 ENSP00000429489
ENST00000521533 ENSP00000430183
ENST00000521093
ENST00000520195
ENST00000517421 ENSP00000431042
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 20 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0047485 protein N-terminus binding
Biological Process
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005869 dynactin complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024603
View Gene Order
ENSBTAG00000015625
Not yet available
Pathways
NETPATH
REACTOME
REACT_121399
MHC class II antigen presentation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
KEGG
hsa05016
Huntington's disease pathway
hsa04962
Vasopressin-regulated water reabsorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.328865 Hs.611506 Hs.675564
RefSeq NM_001135643 NM_001135644 NM_016221
HUGO
OMIM
CCDS CCDS4310 CCDS47310 CCDS47311
HPRD 13126
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca