Version 5.4
Homo sapiens Gene: IFT74
Summary
InnateDB Gene IDBG-55009.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFT74
Gene Name intraflagellar transport 74 homolog (Chlamydomonas)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000096872
Encoded Proteins
IDBP-55011
intraflagellar transport 74 homolog (Chlamydomonas)
IDBP-365526
intraflagellar transport 74 homolog (Chlamydomonas)
IDBP-365530
intraflagellar transport 74 homolog (Chlamydomonas)
IDBP-365535
intraflagellar transport 74 homolog (Chlamydomonas)
IDBP-481284
intraflagellar transport 74 homolog (Chlamydomonas)
IDBP-481866
intraflagellar transport 74 homolog (Chlamydomonas)
IDBP-474798
intraflagellar transport 74 homolog (Chlamydomonas)
IDBP-482968
intraflagellar transport 74 homolog (Chlamydomonas)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:26947039-27062930
Strand Forward strand
Band p21.2
Transcripts
ENST00000380062 ENSP00000369402
ENST00000433700 ENSP00000389224
ENST00000443698 ENSP00000404122
ENST00000429045 ENSP00000393907
ENST00000519968 ENSP00000430004
ENST00000517444 ENSP00000430096
ENST00000518614 ENSP00000430526
ENST00000517866 ENSP00000430742
ENST00000494236
ENST00000482986
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0048487 beta-tubulin binding
Biological Process
GO:0003334 keratinocyte development
GO:0007219 Notch signaling pathway
GO:0008544 epidermis development
GO:0033630 positive regulation of cell adhesion mediated by integrin
GO:0035735 intraciliary transport involved in cilium morphogenesis
GO:0042384 cilium assembly
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050680 negative regulation of epithelial cell proliferation
GO:0060271 cilium morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005813 centrosome
GO:0005929 cilium
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0030992 intraciliary transport particle B
GO:0031514 motile cilium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028576
View Gene Order
ENSBTAG00000019568
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.145402
RefSeq NM_001099222 NM_001099223 NM_001099224 NM_025103
HUGO
OMIM
CCDS CCDS43793 CCDS47955
HPRD 09727
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca