Version 5.4
Homo sapiens Gene: HAVCR1
Summary
InnateDB Gene IDBG-55259.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HAVCR1
Gene Name hepatitis A virus cellular receptor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000113249
Encoded Proteins
IDBP-55261
hepatitis A virus cellular receptor 1
IDBP-477909
hepatitis A virus cellular receptor 1
IDBP-476663
hepatitis A virus cellular receptor 1
IDBP-475585
hepatitis A virus cellular receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:157029413-157059119
Strand Reverse strand
Band q33.3
Transcripts
ENST00000339252 ENSP00000344844
ENST00000522693 ENSP00000428524
ENST00000523175 ENSP00000427898
ENST00000517644
ENST00000518745 ENSP00000428422
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001618 virus receptor activity
GO:0005515 protein binding
Biological Process
GO:0009615 response to virus
GO:0016032 viral process
Cellular Component
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q96D42
TrEMBL E5RIF6
UniProt Splice Variant
Entrez Gene 26762
UniGene Hs.129711
RefSeq NM_001173393 NM_001099414 NM_012206
HUGO HGNC:17866
OMIM 606518
CCDS CCDS43392
HPRD 09404
IMGT
EMBL AC026777 AF043724 BC013325 CR457114
GenPept AAC39862 AAH13325 CAG33395
RNA Seq Atlas 26762

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca