Version 5.4
Homo sapiens Gene: CORO1C
Summary
InnateDB Gene IDBG-55497.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CORO1C
Gene Name coronin, actin binding protein, 1C
Synonyms HCRNN4
Species Homo sapiens
Ensembl Gene ENSG00000110880
Encoded Proteins
IDBP-55499
coronin, actin binding protein, 1C
IDBP-375063
coronin, actin binding protein, 1C
IDBP-382675
coronin, actin binding protein, 1C
IDBP-602940
coronin, actin binding protein, 1C
IDBP-589829
coronin, actin binding protein, 1C
IDBP-596421
coronin, actin binding protein, 1C
IDBP-600376
coronin, actin binding protein, 1C
IDBP-596425
coronin, actin binding protein, 1C
IDBP-601312
coronin, actin binding protein, 1C
IDBP-595213
coronin, actin binding protein, 1C
IDBP-600668
coronin, actin binding protein, 1C
IDBP-601890
coronin, actin binding protein, 1C
IDBP-600168
coronin, actin binding protein, 1C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:108645109-108731596
Strand Reverse strand
Band q24.11
Transcripts
ENST00000261401 ENSP00000261401
ENST00000421578 ENSP00000415554
ENST00000420959 ENSP00000394496
ENST00000541050 ENSP00000438341
ENST00000546705 ENSP00000447337
ENST00000549384
ENST00000550542 ENSP00000448130
ENST00000549772 ENSP00000447534
ENST00000549387
ENST00000552030
ENST00000547361
ENST00000552871 ENSP00000449658
ENST00000547294 ENSP00000449330
ENST00000550032 ENSP00000447989
ENST00000551550 ENSP00000448527
ENST00000546571 ENSP00000448195
ENST00000551044 ENSP00000447049
ENST00000547170
ENST00000551059
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 50 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 50 [view]
Protein-Protein 48 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051015 actin filament binding
Biological Process
GO:0006909 phagocytosis
GO:0007165 signal transduction
GO:0030036 actin cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0015629 actin cytoskeleton
GO:0030027 lamellipodium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000004530
View Gene Order
ENSBTAG00000007993
Not yet available
Cross-References
SwissProt
TrEMBL F8VV53
UniProt Splice Variant
Entrez Gene 23603
UniGene Hs.330384 Hs.715881
RefSeq NM_001105237 NM_001276471 NM_014325
HUGO HGNC:2254
OMIM 605269
CCDS CCDS61236 CCDS9120
HPRD 09244
IMGT
EMBL AC007569
GenPept
RNA Seq Atlas 23603

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca