Version 5.4
Homo sapiens Gene: DACT3
Summary
InnateDB Gene IDBG-58901.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DACT3
Gene Name dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000197380
Encoded Proteins
IDBP-58903
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
IDBP-246730
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
IDBP-294179
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:46647612-46661138
Strand Reverse strand
Band q13.32
Transcripts
ENST00000300875 ENSP00000300875
ENST00000391916 ENSP00000375783
ENST00000410105 ENSP00000387300
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0051018 protein kinase A binding
GO:0070097 delta-catenin binding
Biological Process
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0016055 Wnt signaling pathway
GO:0030178 negative regulation of Wnt signaling pathway
GO:0030308 negative regulation of cell growth
GO:0035414 negative regulation of catenin import into nucleus
GO:0090090 negative regulation of canonical Wnt signaling pathway
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000078794
View Gene Order
ENSBTAG00000030705
Not yet available
Cross-References
SwissProt Q96B18
TrEMBL G5E9H6
UniProt Splice Variant
Entrez Gene 147906
UniGene Hs.515490
RefSeq NM_001301046 NM_145056 XM_005258551
HUGO HGNC:30745
OMIM 611112
CCDS CCDS12688 CCDS74402
HPRD
IMGT
EMBL AC093503 BC016161 BI603646 CH471126
GenPept AAH16161 EAW57439
RNA Seq Atlas 147906

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca