Version 5.4
Homo sapiens Gene: FUT2
Summary
InnateDB Gene IDBG-60943.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FUT2
Gene Name fucosyltransferase 2 (secretor status included)
Synonyms B12QTL1; SE; Se2; SEC2; sej
Species Homo sapiens
Ensembl Gene ENSG00000176920
Encoded Proteins
IDBP-246803
fucosyltransferase 2 (secretor status included)
IDBP-382831
fucosyltransferase 2 (secretor status included)
IDBP-473442
fucosyltransferase 2 (secretor status included)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:48695971-48705950
Strand Forward strand
Band q13.33
Transcripts
ENST00000391876 ENSP00000375748
ENST00000425340 ENSP00000387498
ENST00000522966 ENSP00000430227
ENST00000522283
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity
GO:0008417 fucosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006486 protein glycosylation
GO:0036065 fucosylation
GO:0042355 L-fucose catabolic process
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000055978
View Gene Order
ENSBTAG00000021557
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00601
Glycosphingolipid biosynthesis pathway
hsa00603
Glycosphingolipid biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.579928 Hs.678779
RefSeq NM_000511 NM_001097638
HUGO
OMIM
CCDS CCDS33069
HPRD 01629
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca