InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ACSL1

Summary

InnateDB Gene

IDBG-628536.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ACSL1

Gene Name

long-chain-fatty-acid--CoA ligase 1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000004344

Encoded Proteins

IDBP-679900

long-chain-fatty-acid--CoA ligase 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151726:
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 27:14223449-14288333

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000005684

ENSBTAP00000005684

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004467	long-chain fatty acid-CoA ligase activity

Biological Process

GO:0001676	long-chain fatty acid metabolic process
GO:0008152	metabolic process
GO:0008610	lipid biosynthetic process
GO:0033211	adiponectin-activated signaling pathway
GO:0044539	long-chain fatty acid import
GO:0071902	positive regulation of protein serine/threonine kinase activity