Version 5.4
Bos taurus Gene: PDLIM3
Summary
InnateDB Gene IDBG-628559.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDLIM3
Gene Name PDZ and LIM domain protein 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017183
Encoded Proteins
IDBP-679927
PDZ and LIM domain protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154553:
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 27:14769571-14800205
Strand Reverse strand
Band
Transcripts
ENSBTAT00000022835 ENSBTAP00000022835
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
GO:0008270 zinc ion binding
GO:0008307 structural constituent of muscle
GO:0046872 metal ion binding
Biological Process
GO:0007015 actin filament organization
GO:0007507 heart development
Cellular Component
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
GO:0030018 Z disc
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000154553
View Gene Order
ENSMUSG00000031636
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.57571
RefSeq NM_001034646
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca