Version 5.4
Bos taurus Gene: MAP1B
Summary
InnateDB Gene IDBG-628588.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAP1B
Gene Name microtubule-associated protein 1B
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001961
Encoded Proteins
IDBP-679966
microtubule-associated protein 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131711:
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:9330175-9419040
Strand Reverse strand
Band
Transcripts
ENSBTAT00000002548 ENSBTAP00000002548
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.
Predicted by orthology
Total 50 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0016787 hydrolase activity
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0001578 microtubule bundle formation
GO:0007409 axonogenesis
GO:0008152 metabolic process
GO:0009987 cellular process
GO:0016358 dendrite development
GO:0032387 negative regulation of intracellular transport
GO:0045773 positive regulation of axon extension
GO:0047497 mitochondrion transport along microtubule
GO:0048675 axon extension
GO:0061162 establishment of monopolar cell polarity
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000131711
View Gene Order
ENSMUSG00000052727
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
reelinpathway
Reelin signaling pathway
netrin_pathway
Netrin-mediated signaling events
lis1pathway
Lissencephaly gene (LIS1) in neuronal migration and development
Cross-References
SwissProt
TrEMBL F1N1S2 Q28136 Q28137
UniProt Splice Variant
Entrez Gene 514739
UniGene Bt.37111
RefSeq NM_001206119 XM_005221406
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02050025 Z29519 Z29520
GenPept CAA82639 CAA82640
RNA Seq Atlas 514739

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca